What is it about?
in HIV infection, the viral transmission can occur between host cells and virions, viral clearance occur in CD4+Tcells. The model capture the effect of cell to cell contact and viral clearance by host cells on HIV-1 infection.
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Why is it important?
the effect of clearance by host cell impacts of the progression of HIV-1 infection, when the immune system is still normal, the viral load can be controlled in the body.
Perspectives
I hope this article provide description about the effect of viral transmission through cell-cell contact, and viral clearance by host cell in the progression of HIV infection. The clearance effect determine the progression of HIV infection. HIV-1 infection can be control when the immune system is sill normal.
sutimin sutimin
Universitas Diponegoro
Read the Original
This page is a summary of: Modeling of HIV-1 infection incorporating cell-to-cell transmission and viral clearance of CD4+T cells, January 2020, American Institute of Physics,
DOI: 10.1063/5.0024193.
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