What is it about?
The study of incidence and distribution of health related events including disease, and control of disease are observed through Epidemiology. Toxoplasmosis is an omnipresent protozoan parasite that can infect all warm blood vertebrates, including mammals and birds. The infection is quite vast as approximately 20% human population in US and 30% world-wide are infected by this protozoan parasite. In this study, a mathematical model of interaction between Toxoplasma Gondii invasion dynamics and host immune responses is developed using system of ordinary differential equations. The analytic and numerical simulations are carried out to understand the dynamics and the impact of different functional responses.
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Why is it important?
Toxoplasma has become a global threat as 30%-50% of human population are infected worldwide. This study helps to understand that the Holling type II functional response enhances the effect or cells of host’s immune response. However, it does not influence the reproduction number, force of infection and other parameters during the transient and steady-state of the disease infection. Our results will help to understand the impact of active immune response in host.
Perspectives
This article was based on very different topic of Epidemiology. Most of us are not aware of such kind of infectious diseases. Toxoplasmosis is caused by single cell protozoan parasite that has infected approximately 20% human population in US and 30% world-wide. This research article will help to make people aware of Toxoplasmosis.
Dr. Avinita Gautam
University of Catania, Italy
Read the Original
This page is a summary of: Mathematical modelling of Toxoplasma Gondii and host immune response, January 2018, American Institute of Physics,
DOI: 10.1063/1.5042172.
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