What is it about?
ezetimibe when added to statin therapy does not lower mortality - although it decreases LDL-C. Increasing statin dose decreases LDL but does not lower mortality. Therefore there is no General Agreement on this costly but not helpful therypy.
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Why is it important?
it helps clarifying clinicaal practice with statins
Perspectives
any prophylactic therapy should either decrease symptoms of the disease or lower mortality. If it does not , it should be abandonned
Professor Erland Erdmann
University of Cologne
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This page is a summary of: Was bringt die stärkere Senkung des LDL-Cholesterins durch eine Kombinationstherapie?, DMW - Deutsche Medizinische Wochenschrift, August 2015, Thieme Publishing Group,
DOI: 10.1055/s-0041-103886.
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