What is it about?

A simple and efficient synthetic method for N-aryl putrescines (1,4-butanediamines) and cadaverives (1,5-pentanediamines). It involves selective N-alkylation of anilines with omega-halonitriles followed by reduction.

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Why is it important?

The first general synthesis of N-aryl putrescines (1,4-butanediamines) and cadaverives (1,5-pentanediamines), key intermediates for synthetic polyamine analogues The first cesium mediated selective N-alkylation of anilines reported

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This page is a summary of: An Efficient Synthesis of N-Arylputrescines and Cadaverines, Synlett, February 2009, Thieme Publishing Group,
DOI: 10.1055/s-0028-1087817.
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