What is it about?

At lower lung volumes DLCO becomes smaller as expected from lower surface area for diffusion, and DLCO/VA higher. DACO - adjusting predicted DLCO for lung volume - provides a better indication of diffusion.

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Why is it important?

Knowing the lungs diffusion capacity helps assess lung function

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This page is a summary of: Importance of adjusting carbon monoxide diffusing capacity (DLCO) and carbon monoxide transfer coefficient (K CO) for alveolar volume, Respiratory Medicine, January 2000, Elsevier,
DOI: 10.1053/rmed.1999.0740.
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