Deep Tissue Wavefront Estimation for Sensorless Aberration Correction

What is it about?

When we view into biological tissue our image is aberrated by the tissue. We can correct for these aberrations if we can measure them. Light scattering in biological tissues limits how deep we measure these aberrations. This limits our ability to correct our image. With the knowledge of the refractive index of the tissue, the aberration is estimated by calculating optical path length of rays from the target inside of the samples so that we can correct for it even if we can't measure it directly. Simulations based on different configurations are demonstrated in this paper.

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