What is it about?
Nedd8 is a small protein modifier that can be covalently attached to proteins in a manner similar to that of ubiquitin and SUMO. We identified this deneddylating enzyme through its similarity to the desumoylating enzymes, Ulp1 and Ulp2.
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This page is a summary of: Nep1, a Schizosaccharomyces pombe deneddylating enzyme , Biochemical Journal, July 2005, Portland Press Ltd.,
DOI: 10.1042/bj20041991.
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Resources
Cell-cycle-dependent localisation of Ulp1, a Schizosaccharomyces pombe Pmt3 (SUMO)-specific protease
Our identification of the S. bombe desumoylating enzyme Ulp1
The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2
Our identification and characterisation of the desumoylating enzyme Ulp2
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