What is it about?
This study explores how bromelain, an industrially important enzyme, behaves in a novel solvent called a deep eutectic solvent (DES). By analyzing bromelain's structure, flexibility, and activity in different DES conditions, the researchers show how the solvent environment impacts the enzyme's efficiency.
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Why is it important?
Deep eutectic solvents are environmentally friendly and tunable, making them promising alternatives to conventional solvents in biocatalysis. Understanding how these solvents affect enzyme function could lead to more efficient industrial processes and pave the way for new applications in green chemistry.
Perspectives
This work is exciting because it combines green chemistry with detailed biophysical insights, demonstrating how DESs can enhance or preserve enzyme activity. It's fascinating to see how specific solvent properties, like viscosity and polarity, directly influence protein structure and dynamics, offering a new perspective on sustainable biocatalysis.
Dr. Nilimesh Das
Harvard University
Read the Original
This page is a summary of: Correlating Bromelain's activity with its structure and active-site dynamics and the medium's physical properties in a hydrated deep eutectic solvent, Physical Chemistry Chemical Physics, January 2021, Royal Society of Chemistry,
DOI: 10.1039/d1cp00046b.
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