New catalytic strategy to add fluorine to organic molecules using cheap potassium fluoride salt

What is it about?

A new class of molecules, named hydro-crowns, was proposed as catalysts for nucleophilic fluorination of organic molecules based on high level theoretical calculations.

Featured Image

Why is it important?

Organofluorine compounds corresponds to 20% of pharmaceuticals and 30% of agrochemicals. The new approach based on hydro-crowns catalysis could provide a more effective pathway for fluorination of organic molecules using cheap and easily available potassium fluoride salt as reagent.