What is it about?

In this study, we have utilized the liposomal technology to efficiently deliver maduramicin to Plasmodium-infected RBCs. The developed lipid formulation successfully treated malaria in mice model without any adverse sign of toxicity.

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Why is it important?

Our nanoformulation loaded with maduramicin cured drug-resistant Plasmodium infection in mice.

Perspectives

I believe this article will open new dimensions for malaria chemotherapy. It will provide a broader perspective that how targeted drug delivery can help to find novel means for the treatment of complex human diseases.

Mohsin Raza
University of Delhi

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This page is a summary of: Long circulatory liposomal maduramicin inhibits the growth ofPlasmodium falciparumblood stages in culture and cures murine models of experimental malaria, Nanoscale, January 2018, Royal Society of Chemistry,
DOI: 10.1039/c8nr02442a.
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