What is it about?
In this study, we have utilized the liposomal technology to efficiently deliver maduramicin to Plasmodium-infected RBCs. The developed lipid formulation successfully treated malaria in mice model without any adverse sign of toxicity.
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Why is it important?
Our nanoformulation loaded with maduramicin cured drug-resistant Plasmodium infection in mice.
Perspectives
I believe this article will open new dimensions for malaria chemotherapy. It will provide a broader perspective that how targeted drug delivery can help to find novel means for the treatment of complex human diseases.
Mohsin Raza
University of Delhi
Read the Original
This page is a summary of: Long circulatory liposomal maduramicin inhibits the growth ofPlasmodium falciparumblood stages in culture and cures murine models of experimental malaria, Nanoscale, January 2018, Royal Society of Chemistry,
DOI: 10.1039/c8nr02442a.
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