What is it about?
Thiolated Au18 cluster is bio-compatible and it has demonstrated that is able to adsorb cisplatin molecule(s). The calculated adsorption energy is comprised in the 0.5 - 3.6 eV range and it opens up a new direction into the thiolated gold cluster potential applications
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Why is it important?
The cisplatin is a well known anticancer drug but unfortunately it features side effects due to its loss during it transit toward affected organs or tissues. Our goal is to provide with a nano-carrier able to "transport" cisplatin maintaining cisplatin integrity (amount and structure).
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This page is a summary of: Study of the interaction between cisplatin and the Au18(SR)14 cluster: in search of an appropriate cisplatin carrier, Physical Chemistry Chemical Physics, January 2017, Royal Society of Chemistry,
DOI: 10.1039/c7cp04452f.
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