Metabolic flux pattern of glucose utilization by Xanthomonas campestris pv. campestris: prevalent role of the Entner–Doudoroff pathway and minor fluxes through the pentose phosphate pathway and glycolysis

  • Sarah Schatschneider, Claudia Huber, Heiko Neuweger, Tony Francis Watt, Alfred Pühler, Wolfgang Eisenreich, Christoph Wittmann, Karsten Niehaus, Frank-Jörg Vorhölter
  • Molecular BioSystems, January 2014, Royal Society of Chemistry
  • DOI: 10.1039/c4mb00198b

Metabolic flux in Xanthomonas campestris

What is it about?

Xanthomonas campestris is a bacterium that causes plant diseases. At the same time, it is used to produce a thickening agent called xanthan, which finds more and more applications. It has become a popular additive to food, pharamaceuticals, and technical fluids. We determined which metabolic pathways are used when the sugar glucose is used by Xanthomonas campestris to obtain energy and building blocks for growth and xanthan production.

Why is it important?

A more detailed understanding of how sugars like glucose are utilized by Xanthomonas campestris may help to better understand how xanthan is produced by the bacteria. This may help increasing the efficieny of xanthan production. This data is also useful to understand how Xanthomonas causes plant diseases. The results are particular valuable because Xanthomonas campestris is a model organism for which many other data are already available by scientific publications.

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The following have contributed to this page: Dr Frank Jörg Vorhölter