What is it about?
A rapid, specific and reliable HPLC combined with quadrupole time-of-flight dual electrospray ionization mass spectrometry method has been developed and validated for the identification and characterization of stressed degradation (oxidation and hydrolysis) products of piperine.
Featured Image
Why is it important?
A rapid, specific and reliable high-performance liquid chromatography combined with quadrupole time-of-flight dual electrospray ionization mass spectrometry (LC/Q-TOF-dual ESI-MS) method has been developed and validated for the identification and characterization of stressed degradation products of piperine. Piperine, an anti-hypertensive drug, was subjected to hydrolysis (acidic, alkaline and neutral), oxidation, photolysis and thermal stress, as per ICH-specified conditions.
Read the Original
This page is a summary of: Identification and characterization of stress degradation products of piperine and profiling of a black pepper (Piper nigrum L.) extract using LC/Q-TOF-dual ESI-MS, Analytical Methods, January 2014, Royal Society of Chemistry,
DOI: 10.1039/c4ay01088d.
You can read the full text:
Resources
Contributors
The following have contributed to this page
