A lab-on-chip cell-based biosensor for label-free sensing of water toxicants

  • F. Liu, A. N. Nordin, F. Li, I. Voiculescu
  • Lab on a Chip, January 2014, Royal Society of Chemistry
  • DOI: 10.1039/c3lc51085a

Lab on Chip for Detection of Water Toxicants

What is it about?

An integrated impedance and mass sensor in a fluidic cell culturing well was fabricated to rapidly detect water toxicants. Bovine aortic endothelial cell were used as toxicity sensing cells. The sensor successfully detected different concentrations of ammonia, nicotine and aldicarb.

Why is it important?

Conventional sensors that detect water toxicants are very sensitive but time-consuming and require a well-equipped lab. This miniature lab-on-a-chip allows simplified detection of toxicants by using cells and monitoring how the cell reacts to the toxicants. Measurements can be made rapidly on this miniature and portable device.

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The following have contributed to this page: Anis Nurashikin Nordin