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A variety of logic operations have been designed with pH as an external modulator by choosing a small molecule and a c-kit2 promoter quadruplex as two inputs and fluorescence signals of small molecules as two outputs.
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This page is a summary of: pH dependent multifunctional and multiply-configurable logic gate systems based on small molecule G-quadruplex DNA recognition, Chemical Communications, January 2013, Royal Society of Chemistry,
DOI: 10.1039/c3cc38888c.
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