What is it about?
It has been known for a long time that filamentous actin is a chemical motor; the energy released upon synthesis and breakdown of F-actin is used by the cell to do work like pushing and pulling the membrane. We measured this work indirectly by monitoring the change in membrane force at the tip of an F-actin filled membrane nanotube formed from a living cell.
Featured Image
Why is it important?
Our demonstration that dynamical force measurements at the edge of cells reveals chemical characteristics of the bonds is an important contribution to this field.
Perspectives
Read the Original
This page is a summary of: Measuring forces at the leading edge: a force assay for cell motility, Integrative Biology, January 2013, Oxford University Press (OUP),
DOI: 10.1039/c2ib20097j.
You can read the full text:
Contributors
The following have contributed to this page