Synthesis of the marine natural product antibiotic marinopyrrole B.
What is it about?
Marinopyrrole B is an antibiotic of unusual structure. The structure presents some difficult challenges for synthesis and a method to overcome the challenges was developed.
Why is it important?
Marinopyrrole is active against methicillin-resistant bacteria and the core structure may represent a new pharmacophore for the design of other antibiotics.
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