What is it about?
The study is the first to demonstrate the reversible nature of imine bonds of chitosan in aqueous solutions in which chitosan is soluble.
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Why is it important?
We demonstrate that the imination equilibrium of chitosan shifts toward the products as water is removed from the system. In aqueous solutions, the extent of the shift back to the reactants depends on the nature of the aldehyde, specifically the strength of the imine bonds. This is crucial for developing dynamic biomaterials capable of releasing active components in response to external stimuli.
Perspectives
This study lays the foundation for developing dynamic materials based on chitosan.
Dr. Habil. Luminita Marin
Petru Poni Institute of Macromolecular Chemistry of Romanian Academy
Read the Original
This page is a summary of: Imino-chitosan biodynamers, Chemical Communications, January 2012, Royal Society of Chemistry,
DOI: 10.1039/c2cc34337a.
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