What is it about?

Single particle inductively coupled plasma mass spectrometry (spICP-MS) is an important tool for the characterization of nanoparticles (NPs). The method allows determining the size, size distribution, and particle number concentrations of NPs in suspensions after a mere few minutes of measurement. In this publication, the current status of the field is critically reviewed.

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Why is it important?

This review is ideally suited for the ICP-MS user that wants to get informed about the recent developments in single particle ICP-MS. A comprehensive table gives information on the topics and experimental conditions used in a large number of peer-reviewed studies. Also, this review offers a critical insight into the current limitations of the method and future perspectives.


Single particle and single cell analysis will become an important field of elemental mass spectrometry in the future.

Professor Carsten Engelhard
University of Siegen

Read the Original

This page is a summary of: A critical review of single particle inductively coupled plasma mass spectrometry – A step towards an ideal method for nanomaterial characterization, Journal of Analytical Atomic Spectrometry, January 2020, Royal Society of Chemistry,
DOI: 10.1039/c9ja00206e.
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