Probing transcription factor binding activity and downstream gene silencing in living cells with a DNA nanoswitch

Alessandro Bertucci, Junling Guo, Nicolas Oppmann, Agata Glab, Francesco Ricci, Frank Caruso, Francesca Cavalieri
  • Nanoscale, January 2018, Royal Society of Chemistry
  • DOI: 10.1039/c7nr07814e

What is it about?

The use of DNA-based switch to probe and image the intracellular dynamic processes

Why is it important?

To investigate the biophysical chemistry of live cells


Francesca Cavalieri (Author)
Universita degli Studi di Roma Tor Vergata

This approach is extendable to other DNA binding proteins

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The following have contributed to this page: Francesca Cavalieri