Evaluation of changes in monoamine levels and apoptosis induced by cyfluthrin in rats

Dilek Guvenc, Abdurrahman Aksoy, Ayhan Gacar, Enes Atmaca, Kursad Y. Das, Tolga Guvenc
  • Toxicology Research, January 2014, Royal Society of Chemistry
  • DOI: 10.1039/c4tx00041b

Apoptotic Cell Death and Its Importance in Toxicological Response

What is it about?

Insecticides are widely used all over the world.Acute and chronic toxicity that are occured by a variety of xenobiotic chemicals, radiation and toxins, can cause neurodegenerative diseases, ischemic damage, autoimmune disorders and many types of cancer, which depend on apoptotic processes.We have shown that pyrethroid insecticide causes apoptosis in neuronal cells.

Why is it important?

Cell death and cell death mechanisms are one of the most important elements to focus in toxicological assessment.


Dr Dilek Guvenc (Author)
ondokuzmayis √ľniversity veterinary faculty

There is an etiological link between chronic insecticide exposure and various diseases (such as neurodegenerative diseases and cancer). I think that this study will contribute because the mechanism of disease formation is important in the treatment of diseases.

The following have contributed to this page: Dr Dilek Guvenc and Dr Enes Atmaca