What is it about?

We present a synthetic strategy of C-C bond formation followed by isomerization of the allyl residue using palladium catalysis. We use an approach called a homobimetallic catalysis strategy that employs Pd (0) for the cross-coupling and Pd (II) for the isomerization step. We apply this to a set of haloarenes and also demonstrate the presence of two palladium species in the reaction.

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Why is it important?

In this article we show the importance of using two oxidation states of the same metal to achieve two different reactions simultaneously, in a concept called homobimetallic catalysis. We applied this concept to a cross-coupling C-C bond formation through a Stille strategy, which use Pd (0), with a subsequent isomerization, which employs Pd (II). This concept is important because allow the use of two catalytic system using the same conditions.

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This page is a summary of: A facile and convenient sequential homobimetallic catalytic approach towards β-methylstyrenes. A one-pot Stille cross-coupling/isomerization strategy, Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry, DOI: 10.1039/c4ob00604f.
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