Two for one. Use of one reaction conditions employing two oxidation state palladium conditions.

What is it about?

We present a synthetic strategy of C-C bond formation followed by isomerization of the allyl residue using palladium catalysis. We use an approach called a homobimetallic catalysis strategy that employs Pd (0) for the cross-coupling and Pd (II) for the isomerization step. We apply this to a set of haloarenes and also demonstrate the presence of two palladium species in the reaction.

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Photo by Terry Vlisidis on Unsplash

Photo by Terry Vlisidis on Unsplash

Why is it important?

In this article we show the importance of using two oxidation states of the same metal to achieve two different reactions simultaneously, in a concept called homobimetallic catalysis. We applied this concept to a cross-coupling C-C bond formation through a Stille strategy, which use Pd (0), with a subsequent isomerization, which employs Pd (II). This concept is important because allow the use of two catalytic system using the same conditions.