What is it about?
Natural products from a plant Desmos cochinchinensis are potent aromatase inhibitors, a therapeutic approach for the treatment of breast cancer. The isolated natural products exhibit low cytotoxicity, and they may serve as leads for anti-aromatase drugs.
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Why is it important?
Natural flavans isolated from the plant inhibit aromatase enzyme at nanomolar levels, which are the same levels as those of the currently used drugs.
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This page is a summary of: Flavans from Desmos cochinchinensis as potent aromatase inhibitors, MedChemComm, January 2013, Royal Society of Chemistry,
DOI: 10.1039/c3md00166k.
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