Rapid dissolution of DNA in a novel bio-based ionic liquid with long-term structural and chemical stability: successful recycling of the ionic liquid for reuse in the process

Chandrakant Mukesh, Dibyendu Mondal, Mukesh Sharma, Kamalesh Prasad
  • Chemical Communications, January 2013, Royal Society of Chemistry
  • DOI: 10.1039/c3cc42829j

DNA solubilization

What is it about?

DNA a very delicate molecule and a potential building block material is reported to be soluble in few solvents including water and buffer. But their long term stability is very important upon storage. In this paper we have designed new kinds of plant growth hormone based bio-ionic liquids capable of dissolving DNA upto 3.5% with structural and chemical stability upto six month upon storage under ambient conditions.

Why is it important?

New types of ionic liquids based on bioactive molecules were prepared and substantial amount of DNA was solubilized with long term chemical and structural stability.

The following have contributed to this page: Kamalesh Prasad and Dr Mukesh Sharma