Optimization of triazole-based TGR5 agonists towards orally available agents

Kentaro Futatsugi, Kevin B. Bahnck, Martin B. Brenner, Joanne Buxton, Janice E. Chin, Steven B. Coffey, Jeffrey Dubins, Declan Flynn, Denise Gautreau, Angel Guzman-Perez, John R. Hadcock, David Hepworth, Michael Herr, Terri Hinchey, Ann M. Janssen, Sandra M. Jennings, Wenhua Jiao, Sophie Y. Lavergne, Bryan Li, Mei Li, Michael J. Munchhof, Suvi T. M. Orr, David W. Piotrowski, Nicole S. Roush, Matthew Sammons, Benjamin D. Stevens, Gregory Storer, Jian Wang, Joseph S. Warmus, Liuqing Wei, Angela C. Wolford
  • MedChemComm, January 2013, Royal Society of Chemistry
  • DOI: 10.1039/c2md20174g