Discovery of hydroxamate bioisosteres as KAT II inhibitors with improved oral bioavailability and pharmacokinetics

Jaclyn L. Henderson, Aarti Sawant-Basak, Jamison B. Tuttle, Amy B. Dounay, Laura A. McAllister, Jayvardhan Pandit, Suobao Rong, Xinjun Hou, Bruce M. Bechle, Ji-Young Kim, Vinod Parikh, Somraj Ghosh, Edelweiss Evrard, Laura E. Zawadzke, Michelle A. Salafia, Brian Rago, Ronald S. Obach, Alan Clark, Kari R. Fonseca, Cheng Chang, Patrick R. Verhoest
  • MedChemComm, January 2013, Royal Society of Chemistry
  • DOI: 10.1039/c2md20166f
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