Design of 7-amino-6-chloro-3H-imidazo[4,5-b]pyridine scaffold from 5-chloro-2,4-diaminopyrimidine pharmacophore: identification of potent inhibitors of anaplastic lymphoma kinase

Zeqi Huang, Arup K. Ghose, Weihua Wan, Mangeng Cheng, Bruce D. Dorsey, Gregory R. Ott, Keith S. Learn, Jason C. Wagner, Mark S. Albom, Thelma S. Angeles
  • MedChemComm, January 2012, Royal Society of Chemistry
  • DOI: 10.1039/c2md20061a