Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase

Meiling Lu, Yan Huang, Mark A. White, Xuri Wu, Nan Liu, Xiaodong Cheng, Yijun Chen
  • Chemical Communications, January 2012, Royal Society of Chemistry
  • DOI: 10.1039/c2cc36334h

What is it about?

The mechanism of a unique double reduction catalyzed by a single ketoreductase.

Why is it important?

The stereoselective production of two chiral alchohols involves two active sites in a single enzyme.

Perspectives

Prof. Yijun Chen (Author)
China Pharmaceutical University

Nature is able to do so many unprecedented and suprised reactions to help peoples' life.

The following have contributed to this page: Prof. Yijun Chen