Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency

Fabio Pacchiano, Mayank Aggarwal, Balendu Sankara Avvaru, Arthur H. Robbins, Andrea Scozzafava, Robert McKenna, Claudiu T. Supuran
  • Chemical Communications, January 2010, Royal Society of Chemistry
  • DOI: 10.1039/c0cc02707c