Click chemistry with DNAAfaf H. El-Sagheer, Tom Brown
- Chemical Society Reviews, January 2010, Royal Society of Chemistry
- DOI: 10.1039/b901971p
Click Chemistry on DNA
What is it about?
A review of publications on DNA click chemistry; methods to join together nucleic acids chemically and to label them with reporter groups such as fluorescent dyes.
Why is it important?
A new paradigm in nucleic acid chemistry enabling the synthesis of modified nucleic acids and DNA and RNA analogues that could not previously be made.