What is it about?
An X-ray cristal of the drug variolin B intercalating DNA was obtained. This revealed the origin of its potent inhibitory activity of the growth of human tumor cells in vitro
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Why is it important?
Because confirm theory that variolin B acts as DNA intercalator
Perspectives
Useful for the scientific comunity
Professor Mercedes Álvarez
Universitat de Barcelona
Read the Original
This page is a summary of: Intercalative DNA binding of the marine anticancer drug variolin B, Scientific Reports, January 2017, Nature,
DOI: 10.1038/srep39680.
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