What is it about?
Ergodicity breaking on the neuronal surface.
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Why is it important?
Often the complexity of the cell membranes leads to anomalous diffusion, which under certain conditions it is accompanied by non-ergodic dynamics. Here, we unravel two manifestations of ergodicity breaking in the dynamics of membrane proteins in the somatic surface of hippocampal neurons. First, significant differences are observed between time- and ensemble-averaged MSD. Second, a dynamical functional test unmasks ergodicity breaking at the individual trajectory level.
Perspectives
Ergodicity breaking is found to take place due to transient confinement effects since the molecules alternate between free diffusion and confined motion.
Aleksander Weron
Politechnika Wroclawska
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This page is a summary of: Estimating the anomalous diffusion exponent for single particle tracking data with measurement errors - An alternative approach, Scientific Reports, June 2015, Springer Science + Business Media,
DOI: 10.1038/srep11306.
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