What is it about?

Urate exporter ABCG2's variants affects both types (classification) of hyperuricemia/gout; ROL and RUE types

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Why is it important?

In both kidney and intestine, ABCG2 plays an important role for urate excretion.

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This page is a summary of: ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload, Scientific Reports, January 2014, Nature,
DOI: 10.1038/srep03755.
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