What is it about?

In this work, we show clear evidences of a porous sylvatic-domiciliary transmission interface and ongoing adaptation of P. geniculatus to the urban ecotope. Although P. geniculatus defecation traits greatly limit the possibility of active T. cruzi transmission for any individual biting event, the cumulation of this low risk across a vast metropolitan populationwarrants further investigation. Efforts to prevent triatomine contact with human food sources also clearly require greater attention to protect Venezuela’s capital from Chagas disease

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Why is it important?

Results compel greater attention toward Chagas disease surveillance in Caracas. A human serological survey for T. cruzi, especially in the pediatric population, would help clarify the consequences of triatomine infection and human-triatomine contact events demonstrated from this study’s citizen sciencebased datase

Perspectives

A systematic human serological survey for T. cruzi occurrence in the MDC is important to this end. Other important investigative and precautionary measures include developing a better understanding of domiciliary niches where triatomine reproduction occurs, reducing urban T. cruzi reservoir populations, promoting housing materials that reduce triatomine intrusion, tracking and intervening against patterns of parasite-food source contamination, further educating the public on Chagas disease epidemiology, and increasing cognizance among medical workers towards the possibility of acute T. cruzi infection and associated clinical profiles. All of these objectives are especially challenging in Venezuela’s current socioeconomic situation, and broad support in funding and resources is key

Dr. Hernán José Carrasco
Universidad Central de Venezuela

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This page is a summary of: Multilocus analysis uncovers the evolution of the Rhodniini tribe, vectors of Trypanosoma cruzi, Scientific Reports, July 2025, Springer Science + Business Media,
DOI: 10.1038/s41598-025-03789-9.
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