What is it about?
The article explores the genetic differences in drug metabolizing enzyme and transporter genotypes and discusses most pertinent and important therapeutic implications among a major proportion of South Asian population, that is yet unexplored.
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Why is it important?
Knowing such differences would enable an understanding of therapeutic outcomes in this population and thus would help attain the goal of personalized medicine.
Perspectives
This is a landmark study in the region and informs about a large yet understudied population.
Dr Nasir Ali Afsar
Jinnah Medical & Dental College Karachi; Alfaisal University Riyadh.
Read the Original
This page is a summary of: Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani Population, Scientific Reports, May 2019, Springer Science + Business Media,
DOI: 10.1038/s41598-019-43736-z.
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