What is it about?

to estimate the prevalence of VKORC1, CYP2C9, and CYP4F2 genetic variants and their contribution to warfarin dose variability in Qataris

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Why is it important?

VKORC1 (−1639G>A), CYP2C9*2 & *3 are the most significant predictors of warfarin dose along with HTN, HF and smoking.

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This page is a summary of: The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population, The Pharmacogenomics Journal, October 2019, Springer Science + Business Media,
DOI: 10.1038/s41397-019-0116-y.
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