Disruptive Strategies for Removing Drug Discovery Bottlenecks

  • Sean Ekins, Chris Waller, Mary Bradley, Antony Williams
  • Space Resolver 16, March 2012, Springer Science + Business Media
  • DOI: 10.1038/npre.2012.6961.1

drug discovery bottlenecks

What is it about?

Drug Discovery is shifting focus from the industry to outside partners and in the process creating new bottlenecks, suggesting the need for a more disruptive overhaul. We suggest there needs to be an awareness of what research is going on in the academic screening centers, more collaboration and coordination. These efforts will shift the focus to finding the best researchers to fund and require a rethink of how to reward their collaborative efforts.

Why is it important?

This opinion was later expanded and published by DDT. The emphasis here was using computational approaches to predict safety and efficacy.


Dr Sean Ekins
Collaborations in Chemistry

This publication was one of my earliest experiments in prepublication. Nature Precedings closed soon after in 2012. I personally think this was a mistake to close it http://precedings.nature.com/ and perhaps others benefited from this. Additional experiments in this area include using Figshare recently to post preprints as well as publishing in F1000Research.

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The following have contributed to this page: Dr Antony John Williams and Dr Sean Ekins