What is it about?

This is a review detailing the multiple ways the actin cytoskeleton controls the trafficking and secretion of insulin from pancreatic islet beta cells.

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Why is it important?

1. Understanding insulin secretion is critical for developing diabetes therapeutics. 2. The cytoskeleton controls secretion of insulin, but also other hormones secreted from different cell types. Therefore, gaining understanding of how beta cells secrete insulin will have impacts on other endocrine systems.

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This page is a summary of: Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells, Experimental & Molecular Medicine, August 2013, Springer Science + Business Media,
DOI: 10.1038/emm.2013.73.
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