Characterization of a Setup to test the Impact of High-Amplitude Pressure Waves on Living Cells

Mischa Schmidt, Ulf Kahlert, Johanna Wessolleck, Donata Maciaczyk, Benjamin Merkt, Jaroslaw Maciaczyk, Jens Osterholz, Guido Nikkhah, Martin O. Steinhauser
  • Scientific Reports, January 2014, Springer Science + Business Media
  • DOI: 10.1038/srep03849

What is it about?

This is the first publication presenting our systematic research on the laser-induced shock wave destruction of human cancer cells (U87 glioblastoma). We could proof a convincing biological destructive effect in the cancer cells due to shock wave treatment. This Nature paper describes our research approach and the systematic measurement of the necessary pressure levels to achieve destruction of cancer cells.

Why is it important?

The laser-induced destruction of cancer cells might allow for additional therapies for cancer treatment in the long run. Admittedly, however, our study presented here, constitutes pure fundamental research on standard cell lines and the major step to tissue or even basic organisms would still be huge.

Perspectives

Priv.-Doz. Dr. habil. Martin O. Steinhauser
Fraunhofer-Gesellschaft zur Forderung der angewandten Forschung eV

This was top-notch research work ("stellar work" as a chairman at a conference once put it). Unfortunately, the interest of our institute's management in this fundamental research changed, and so our groundbreaking successful work was voided in the end. A big bummer !

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http://dx.doi.org/10.1038/srep03849

The following have contributed to this page: Priv.-Doz. Dr. habil. Martin O. Steinhauser