What is it about?
Current diagnostic methods rely on blood glucose measurements, which are noninformative with respect to progression of the disease to other associated pathologies. Thus, predicting the risk and development of T2DM-related complications, such as cardiovascular disease, remains a major challenge. we used proteomic approach to identify protein related to diabeteic complications in type 2 DM.
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Why is it important?
These putative biomarkers may be clinically useful for subset stratification of T2DM patients as well as for the development of novel therapeutics targeting the specific pathology.
Perspectives
to apply such putative biomarkers in chort of type 2 DM.
Dr Nasser M Rizk
Mansoura University
Read the Original
This page is a summary of: iTRAQ-Based Quantitative Protein Expression Profiling and MRM Verification of Markers in Type 2 Diabetes, Journal of Proteome Research, November 2012, American Chemical Society (ACS),
DOI: 10.1021/pr300798z.
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