Recyclablel-Proline Functional Nanoreactors with Temperature-Tuned Activity Based on Core–Shell Nanogels

Annhelen Lu, Dafni Moatsou, Ian Hands-Portman, Deborah A. Longbottom, Rachel K. O’Reilly
  • ACS Macro Letters, December 2014, American Chemical Society (ACS)
  • DOI: 10.1021/mz500704y

Exploiting the LCST of PNIPAM for the recycling of polymer-embedded organocatalysts

What is it about?

Polymer particles have been proven excellent candidates as hosts for organocatalysts, in some cases enhancing the efficiency of the catalyst. Here, we demonstrate the use of crosslinked hydrophobic nanogels, that are covalently loaded with L-proline, as an efficient catalytic nanoreactor that can be recycled owing to a temperature-responsive polymeric corona. In addition to that, when the outer polymer layer is not heavily crosslinked, the catalytic efficiency decreases.

Why is it important?

This paper extends the idea of embedding a precious catalyst (here we use L-proline as the cheaper analogue) within an polymer nanoparticle which is easy to make and can easily be separated from smaller molecules, such as the products of the catalysis. In addition to that, we use a polymer that responds to temperature changes, thus making the particles recyclable; that is after removal of the catalysis products, the particles are redispersed and reused.

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http://dx.doi.org/10.1021/mz500704y

The following have contributed to this page: Dr Dafni Moatsou