Applying a machine learning model for metabolic stability
What is it about?
Trying to improve an antitubercular that has metabolic stability problems using a machine learning model. This work combined building a library of virtual analogs and scoring them then making the compounds and testing the metabolic stability.
Why is it important?
This study showed the real difficulty of trying to optimize the whole cell activity and metabolic stability in parallel.
The following have contributed to this page: Dr Sean Ekins