What is it about?

Anisotropic metal nanostructures (e.g. Au–Ag, Au–Cu) have been emerging for biomedical and catalytic applications in recent years. Herein, we report a modified synthesis of Cu-Au tripods for photothermal based anticancer therapy through the controlled nucleation and growth of nanocrystals, and judicious purification of nanocrystals.

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Why is it important?

The distribution of nanocrystals in tripod was analysed by STEM–EDX mapping, indicating the formation of Cu-Au alloy nanocrystals. Simulation using DFT calculations showed the possible formation of alloy structures of nanocrystals such as Cu3Au, Cu-Au and CuAu3 and confirmed that the stability of nanocrystals increased in the following order: CuAu3 < Cu-Au < Cu3Au.


These stable Cu-Au tripods exhibited a well pronounced photothermal effect as demonstrated by experimental and simulation photothermal studies. Cancer cells treated with nanocrystals upon NIR laser exposure showed promising therapeutic effects.

Dr. Sitansu Sekhar Nanda
Myongji University

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This page is a summary of: Experimental and Theoretical Structural Characterization of Cu-Au Tripods for Photothermal Anticancer Therapy, ACS Applied Nano Materials, June 2019, American Chemical Society (ACS),
DOI: 10.1021/acsanm.9b00634.
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