What is it about?
A small molecule ligand for AphB was identified by virtual screening and characterized by STD-NMR. The small molecule was shown to be an activator for AphB.
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Why is it important?
The identification of the small molecule ligand opens the way for the development of inhibitors of AphB
Perspectives
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This page is a summary of: Identification of a Small Molecule Activator for AphB, a LysR-Type Virulence Transcriptional Regulator in Vibrio cholerae, Biochemistry, July 2017, American Chemical Society (ACS),
DOI: 10.1021/acs.biochem.7b00337.
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