What is it about?

insertion of N-tosylacetimidates and N-tosyl-acetimidamides onto various substituted benzynes is reported.

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Why is it important?

Tunable reactivity of 2-sulfonamidoindoles was explained with mechanistic studies.


various benzoic acid derivatives were synthesized using the aryne insertion strategy.

Dr. Kranthi Kumar Ramagonolla
Harvard University

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This page is a summary of: Insertion of N-Tosylacetimidates/Acetimidamides onto Arynes via [2 + 2] Cycloaddition, The Journal of Organic Chemistry, March 2016, American Chemical Society (ACS), DOI: 10.1021/acs.joc.5b02907.
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