Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1)

  • Matthäus Getlik, David Smil, Carlos Zepeda-Velázquez, Yuri Bolshan, Gennady Poda, Hong Wu, Aiping Dong, Ekaterina Kuznetsova, Richard Marcellus, Guillermo Senisterra, Ludmila Dombrovski, Taraneh Hajian, Taira Kiyota, Matthieu Schapira, Cheryl H. Arrowsmith, Peter J. Brown, Masoud Vedadi, Rima Al-awar
  • Journal of Medicinal Chemistry, March 2016, American Chemical Society (ACS)
  • DOI: 10.1021/acs.jmedchem.5b01630

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http://dx.doi.org/10.1021/acs.jmedchem.5b01630