ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology

  • Ann M. Richard, Richard S. Judson, Keith A. Houck, Christopher M. Grulke, Patra Volarath, Inthirany Thillainadarajah, Chihae Yang, James Rathman, Matthew T. Martin, John F. Wambaugh, Thomas B. Knudsen, Jayaram Kancherla, Kamel Mansouri, Grace Patlewicz, Antony J. Williams, Stephen B. Little, Kevin M. Crofton, Russell S. Thomas
  • Chemical Research in Toxicology, July 2016, American Chemical Society (ACS)
  • DOI: 10.1021/acs.chemrestox.6b00135

What is it about?

The U.S. Environmental Protection Agency’s (EPA) ToxCast program is testing a large library of Agency-relevant chemicals using in vitro high-throughput screening (HTS) approaches to support the development of improved toxicity prediction models. The history of the phased construction of EPA’s ToxCast library is reviewed, followed by a survey of the library contents from several different vantage points.

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The following have contributed to this page: Dr Antony John Williams, Dr John Fredrick Wambaugh, Dr kamel mansouri, and Jayaram Kancherla