What is it about?

The aim of this study was to investigate the effects of crotamine, using different exposure times and concentrations, on the quality of in vitro fertilized bovine embryos to assess developmental competence and gene expression.

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Why is it important?

These results indicate that crotamine can translocate intact in vitro fertilized bovine embryos and its application in the culture medium is possible at concentrations from 0.1–10 M for 6–24 h.

Perspectives

Crotamine could be a new method for the production of transgenic animals.

Dr Vicente J Freitas
Universidade Estadual do Ceara

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This page is a summary of: Effect of crotamine, a cell-penetrating peptide, on blastocyst production and gene expression of in vitro fertilized bovine embryos, Zygote, December 2014, Cambridge University Press,
DOI: 10.1017/s0967199414000707.
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