Role of pentacyclic triterpenes in anti-parasitic drug discovery

What is it about?

Petacyclic triterpenoids have potent pharmacological activities. We reviewed tens of pentacyclic triterpenoids tested by different researchers on various neglected parasitic diseases. Relevant analyses and conclusions were made from the generated data.

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Why is it important?

Parasitic diseases especially those in the tropical regions affect mainly the poor populations. Discovery of safer, cheaper and more potent agents against this diseases is in dire need. Therefore, as much information as possible is needed to identify these bioactive compounds either from natural or synthetic sources. The article will serve as a compiled repository of PTs for use of researchers (as well as relevant agencies) working with this group of molecules against parasitic infections.