What is it about?

There are a large number of fair to excellent vaccines for protozoal diseases of animals, but none for people. Animal vaccines are based on classical principles, but vaccine research for malaria has predominantly emphasized novel concepts rather than classical principles.

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Why is it important?

Design categories of protozoal vaccines are described and compared in tables. Analyses are offered to explain the disparity between the number of successful animal vaccines and the lack of human vaccines. Collective evidence indicates that whole organism protozoal vaccines are effective, and these types of vaccines should be developed for malaria.

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This page is a summary of: Successful vaccines for naturally occurring protozoal diseases of animals should guide human vaccine research. A review of protozoal vaccines and their designs, Parasitology, January 2014, Cambridge University Press,
DOI: 10.1017/s0031182013002060.
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